CAPECITABINE 154361-50-9

USP 34 , Medical Grade

  • Product Detail

Product Information

 

Product name

Capecitabine

Molecular Formula

C15H22FN3O6

Molecular Weight

359.35

CAS No.

154361-50-9

Quality Standard

USP34, medical grade

Appearance

White powder

 

COA of CAPECITABINE

 

Items

Specifications

Results

Apperance

White or off-white crystalline powder

White crystalline powder

Identification

The spectrum of the sample corresponds to that of RS

Meets the requirements

 

The retention time of the major peak of the test solution corresponds to that of the RS

Meets the requirements

Specific Rotation

+96.0°~+100.0°

+98.1°

Water

≤0.3%

0.01%

Heavy Metals

≤20ppm

<20ppm

(as Pb)

Residue on ignition

≤0.1%

0.02%

Assay

98.0%~102.0%

99.70%

 

 

Usage

 

Function of Capecitabine

 

Capecitabine is rapidly absorbed through the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5'fluorocytidine in the liver by carboxylesterase, and then decellularized by the liver and tumor The action of ammonia enzyme is converted into 5'-deoxy-5 'fluorouridine, and finally catalyzed by thymidine phosphorylase into fluorouracil (5-FU) in tumor tissue.

Clinical studies have shown that the concentration of 5-FU in tumor tissue after oral administration of this product is significantly higher than blood and muscle levels. The curative effect on various animal tumors is significantly higher than that of 5-FU. This product has a synergistic effect with a variety of anti-tumor drugs.

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